Medical / Laboratory

Cold Chain Basics

The cold chain is the unbroken sequence of temperature-controlled storage and transport that keeps a product within its required range from origin to destination.

Where dry ice fits

Dry ice provides deep-frozen conditions without electricity, which is useful for shipping and backup.

Weak points

Hand-offs, delays and packaging errors are where cold chains usually fail. Plan for delays with buffer ice.

Dry ice releases carbon dioxide gas and requires proper ventilation. Handle only with insulated gloves, and never seal it in an airtight container.

Last reviewed: September 2026

Related tool

Dry Ice Shipping Planner

Plan dry ice for a shipment.

Related product

5/8" Dry Ice Pellets

Versatile pellets for cold-chain shipping, food, medical and industrial use.

View products Find your nearest location

Ready for dry ice?

Tell us what you need and the PA Dry Ice team will confirm availability and next steps.